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Correlation between SPARC (Osteonectin) expression with immunophenotypical and invasion characteristics of pituitary adenomas
Onoz, Mustafa; Başaran, Recep; Güçlüer, Berrin; Işık, Nejat; Kaner, Tuncay; Sav, Aydın; Elmacı, İlhan (Blackwell Munksgaard, 2015)Pituitary adenomas are the third most common intracranial tumors. Invasive adenomas account for only 0.1-0.2% of pituitary tumors. SPARC is a matrix glycoprotein that plays a role in progression and invasiveness of neoplasms. ... -
The role of a single nucleotide polymorphism of the matrix metalloproteinase-1 gene promoter region in invasion and prognosis of meningiomas
Efendioğlu, Mustafa; Başaran, Recep; Bayrak, Ömer Faruk; Işık, Nejat; Kaner, Tuncay; Şahin, Fikrettin; Güçlü, Bülent; Elmacı, İlhan (Turkish Neurosurgical Society, 2014)AIM:The matrix metalloproteinase (MMP) enzyme family has been shown to be active in tumorigenesis and tumor progression. In this study, we analyzed the prevalence of a guanine insertion in the MMP-1 gene promoter region ...